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Syndecan
Definition 1
The syndecans are a family of cell-surface heparan sulphate proteoglycans that regulate cell behavior by binding extracellular matrix molecules such as growth factors. The syndecan family has four members, of which syndecan-1 is the most studied and best characterized. In squamous cell carcinoma of the head and neck low syndecan-1 expression has been associated with unfavorable overall survival and can be used as a prognostic factor. (NCI Thesaurus)
Definition 2
family of transmembrane heparan sulfate proteoglycans. (NIH CRISP Thesaurus)
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